Lokon Pharma

Next generation cancer immunotherapeutics

Our solution

LOKON001

Phase I/II study for pancreatic cancer

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Ongoing

LOKON002

Phase I/II study for patients with pancreatic-, biliary-, ovarian-, and colorectal cancer.

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Completed

LOKON003

Phase I/II study for patients with malignant melanoma.

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Completed

Pipeline

The LOAd family includes a range of novel tumor microenvironment (TME) gene engineering vectors with different immunostimulatory genes that are currently being evaluated for mechanisms-of-action (MOA) and proof-of-concept (POC).

See our pipeline

For patients

If you live in the US and have pancreatic cancer or melanoma, you may be eligible for inclusion in our clinical trials LOKON001 or LOKON003. If you live in Sweden and have pancreatic cancer, melanoma, or ovarian cancer, you may be eligible for inclusion in our clinical trials LOKON002 or LOKON003. If you are interested to participate as a study patient in our trials, please, discuss with your treating physician.

About Lokon

Lokon Pharma is a Swedish biotech company in the forefront of developing tumor microenvironment (TME) gene engineering vectors for cancer. Innovative gene engineering, solid expertise in cancer biology and immunology, as well as a genuine curiosity in life science expand Lokon’s pipeline towards groundbreaking new therapeutics for patients with high unmet medical need.

News

November 4, 2024

Lokon Pharma Announces Collaboration to Combine its TME Gene Engineering Product with Anti-PD-1 Antibody Tislelizumab in Pancreatic Cancer

March 26, 2024

Results from first pancreatic cancer trial using immunostimulatory gene therapy is published in Lancet Oncology

January 12, 2022

Lokon Pharma Initiates a Collaboration with Affibody to Develop Novel Cancer Therapeutics

August 28, 2020

Lokon Pharma Expands Collaboration with Roche Evaluating LOAd703 Immunostimulatory Gene Cancer Therapy in Combination with Tecentriq® (atezolizumab) into Colorectal Cancer

June 3, 2019

Lokon Pharma Announces Collaboration to Combine LOAd703 Oncolytic Virotherapy with Checkpoint Blockade in Pancreatic Cancer and Melanoma

January 19, 2017

First Patient Treated by a Novel Oncolytic Virus Armed with Immune Stimulators

May 19, 2023

Dr Mohamed Hammad, City of Hope, presented our collaboration project using neural stem cells as cell delivery vehicles of Lokon’s LOAd703 at the American Society for Gene and Cell Therapy (ASGCT) in Los Angeles. Stay tuned for the upcoming paper!

October 28, 2022

Jessica Wenthe is presenting her PhD thesis entitled "LOAd703 and beyond - Advancing immunostimulatory gene therapy for cancer" at Rudbeck hall, Rudbeck laboratory, Uppsala University.

September 28, 2022

Preliminary data from LOKON002, LOAd703 treatment of solid malignancies will be presented by Dr Emma Eriksson, Head of R&D at CICON.

Media

Malou efter 10

Bengt fick aggressiv cancer - hade ett år kvar att leva

Barncancerfonden

Immunterapi på 100 sekunder

Malou efter 10

Forskarna om cancervaccinet: ”Behövs pengar”

Uppsala universitet

Immunterapi är ett nytt sätt att bekämpa cancer.

Forskarpodden

Virus som dödar cancer